Israeli Deep-Tech · Longevity Biotechnology

Engineering
Biological Time

The infrastructure layer of longevity.

ChayimTech builds the measurement-and-modulation platform for cellular aging — chromosome-resolved biological-age sensing on long-read sequencing, paired with transient mRNA signaling. Plus elite R&D services through ChayimTech Labs.

Explore the science Request investor materials
The Opportunity

Aging is the most valuable unsolved problem in medicine.

It is the root driver of degenerative disease, spiraling healthcare cost and declining biological productivity — yet there is no programmable, scalable infrastructure layer targeting the mechanisms of cellular aging. The market is fragmented across supplements, clinics and consumer labels.

$27.6B → $67B
Longevity market, 2025 → 2035 (9.4% CAGR)
12.5%
Fastest-growing segment: aging-clock & biomarker technologies
$279B → $957B
Broader AgeTech / silver economy by 2034
Core Thesis

You cannot control what you cannot measure.

Aging is progressive regulatory drift at the cellular level. ChayimTech is built as a two-layer platform.

Measure

Biological-age sensing

A chromosome-resolved telomere clock on long-read sequencing — the diagnostic that proves whether any intervention is actually working.

Modulate

Reversible mRNA signaling

Transient mRNA constructs targeting age-associated pathways — mitochondrial function, stress resilience, repair. Controlled and reversible, not permanent gene editing.

Proprietary Insight

The standard aging biomarker is broken — and we can fix it.

Telomere length is the most-used molecular proxy of cellular aging, but nearly every assay reports a qPCR-derived average — collapsing rich, chromosome-specific biology into a single number.

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ultra-short telomeres are enough to push a cell into senescence — yet a mean length averages them away.

Published — not our claim.
1
The short-telomere tail drives senescence.Averaging hides exactly the signal that matters — breaking TL's validity as a biomarker.
2
Long reads observe the full distribution, per chromosome arm.Only Nanopore-class data can resolve this at scale.
3
We build a T2T-based telomere aging clock from distributions, not scalars.A measurement competitors structurally cannot match.
The Evidence

We didn't invent this thesis. The literature did.

Three independent, peer-reviewed findings make our approach the obvious next step — we are building the clock that operationalizes them.

1

The shortest telomere sets the clock

It is the single shortest telomere — not the average — that triggers replicative senescence and a DNA-damage response.

Hemann et al., Cell 2001 · Abdallah et al., Nat Cell Biol 2009
2

Mean TL is a weak biomarker

Average telomere length is, at best, a rough estimate of aging; ultra-short-telomere load predicts senescence far better.

Vaiserman & Krasnienkov, Front. Genet. 2020
3

Long reads resolve it — on Nanopore

Oxford Nanopore long-read sequencing now measures chromosome- and allele-specific telomere lengths, reproducibly, at scale.

Sanchez et al., Nat. Commun. 2024 (Telo-seq)
Platform Architecture

Three pillars that make this infrastructure.

1

Modular mRNA library

Systematic construct design targeting defined aging pathways — a reusable, expandable toolkit rather than one drug.

2

Biomarker-driven validation

Every construct judged against quantitative, data-guided readouts — including our own biological-age clock.

3

Reversible signaling

Temporary modulation without permanent genomic alteration — controllable and safety-aligned.

ChayimTech Labs · Revenue Engine

A paying R&D arm de-risks the moonshot.

ChayimTech Labs sells elite biotech R&D — experimental design, validation and proof-of-concept — to pharma and platform partners, generating revenue and credibility while the therapeutic platform matures.

First target engagement

Oxford Nanopore

Our first outreach is to the Applications team at Oxford Nanopore Technologies (LSE: ONT), to evaluate a chromosome-resolved telomere clock on real cohorts — a new cohort-scale application for their platform and external validation for ours.

Services
  • Experimental design & proof-of-concept
  • Molecular & assay validation
  • Longevity and oncology research programs
  • Scientific due diligence for investors

More than a CRO: founder-level scientific partnership.

Competitive Position

The giants chase reprogramming. We own measurement + capital efficiency.

Cellular-reprogramming leaders are extraordinarily well funded but capital-intensive and measurement-blind. ChayimTech enters at the earliest layer — quantifying biological age — with a fraction of the capital.

CompanyApproachFunding / valuation
Altos LabsPartial cellular reprogramming~$5B raised
Retro BiosciencesReprogramming + autophagy~$5B valuation ($1B round)
NewLimitEpigenetic reprogramming~$1.62B valuation
ChayimTechMeasurement + reversible mRNA modulationCapital-efficient
How we're built

Lean by design.

A focused core assembles a vetted crew of senior scientists for each program. The same model powers ChayimTech Labs — world-class R&D scaled to the project, without the fixed overhead of a traditional CRO.

DK

Dami Katz

CEO & Founder

Sets the vision, raises and deploys capital, coordinates regulatory strategy, and assembles the scientific crew behind each program.

The bench · senior scientists engaged per program

Molecular cell biology

Weizmann Institute

Senescence, p53 and cancer cell biology — experimental design and validation.

High-content screening

Tel Aviv University

Cell-screening and assay execution for translational programs.

mRNA design

Construct engineering

mRNA molecular design and aging-pathway architecture.

Advisors  Levi Shapiro — Founder, mHealth Israel; Managing Partner, Life Science Vision Capital  ·  Dr. Vered Bar — CureResponse  ·  strategic VC partner (Argentina), closing.

For Investors & Partners

Building the control layer of longevity.

We're raising a seed round and opening our first research engagements. Investor materials available on request.

Contact

Partner with us.

Leave your details and we'll get back to you — for investment, scientific collaboration, or a research program.

Emailinfo@chayimtech.com
Direct line+972 53 351 4742
LocationTel Aviv, Israel
Webchayimtech.com

For investors, scientific collaborators, and pharma / platform R&D clients.